Methods : liver dcs were isolated without expansion in cytokines from human liver allowing us to study unmanipulated tissue - resident dcs ex vivo 方法:从人肝脏中没有表达细胞因子肝树状突细胞被分离出来,允许我们在体外研究未经过处理的组织原位的树状突细胞。
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Conclusions : in hcv - infected liver the combination of enhanced mdc function and a reduced number of pdcs may contribute to viral persistence in the face of persistent inflammation 结论:在hcv感染的肝脏中,增强的髓样树状突细胞功能和降低的浆细胞样树状突细胞的数量的联合可能促成在持久炎症的面前的病毒持续感染。
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Conclusions : this study opened a new field of application of antigen - pulsed dcs for prophylactic purposes when adequate levels of protective antibody cannot be induced by traditional vaccination approaches 结论:该研究开辟了负载抗原的树状突细胞、新的、作为预防用的应用领域,当足够的保护性抗体水平通过传统的接种方法不能被诱导时。